New York University Cotellic Essay

Assignment: Cobimetinib (Cotellic) is an inhibitor of the mitogen-activated protein kinase (MAPK)/extracellular signal regulated kinase 1 (MEK1) and MEK2. These proteins are upstream regulators of the extracellular signal-related kinase (ERK) pathway, which promotes cellular proliferation. BRAF is a member of the Raf kinase family of growth signal transduction protein kinases. This protein plays a role […]