GCU Cancer Genetics & Health Insurance Portability Discussion Nursing Assignment Help

Cancer, Genetics, and Genomics

Rachel comes from a family with a history of breast cancer on her
mother’s side. Rachel’s mother died of breast cancer when she was very
young. Rachel has two sisters, Lisa and Kristin. Rachel has remained
close to Lisa, but she no longer has a relationship with Kristin. At a
routine checkup, Rachel is told about the availability of genetic
testing for identifying a predisposition to breast cancer. Her doctor
recommends the test to Rachel given her family history. Rachel has the
genetic testing done and finds that she has a mutated breast cancer 1,
early onset (BRCA1) gene. Her doctor tells her she is at high risk for
developing breast and ovarian cancer. Rachel’s doctor suggests she ask
her sisters to be tested also, so they can take the proper preventative
measures. Rachel feels comfortable sharing this information with Lisa,
but she has not spoken to Kristin in many years. Rachel tells her doctor
that she is not in contact with Kristin and will not make an effort to
tell her about BRCA1 and genetic testing. Rachel’s doctor feels
confident that she can locate Kristin but worries about breaching
patient confidentiality if she goes against Rachel’s wishes.

If you were Rachel’s healthcare provider, what would you do? Provide a
rationale for your response. Include the pathological processes
associated with breast cancer. What role does the BRCA1 gene contribute
to managing the patient’s care? Describe and explain the role of the
BRCA1 and breast cancer 2, early onset (BRCA2) gene in contribution as a
risk factor for breast cancer. Analyze the risk factors for breast
cancer and possible interventions to preventive health management for
women and men.

Expert Solution Preview

As Rachel’s healthcare provider, it is important to prioritize her overall well-being and provide her with the necessary information and support to make informed decisions about her health. In this case, Rachel has been identified as having a mutated BRCA1 gene, which puts her at a high risk for developing breast and ovarian cancer. Given her family history, it is essential to address the potential risk to her sisters as well.

To handle this situation, I would respect Rachel’s decision not to reach out to her sister Kristin directly. However, I would explain to Rachel the importance of informing her sisters about the genetic testing and the significance of their family’s history of breast cancer. I would educate Rachel about the possible preventive measures and interventions available for individuals with a high-risk BRCA1 mutation, such as increased surveillance, prophylactic surgeries, or chemoprevention options. Stressing the potential for early detection and better outcomes could be beneficial in encouraging Rachel to reconsider.

Regarding patient confidentiality, I would explain to Rachel that it is my responsibility as her healthcare provider to prioritize her health and that of her family members. While patient confidentiality is crucial, there are circumstances where breaching confidentiality is ethically justified, such as when it concerns the well-being of others in the family. In this case, sharing the information with her sister would be an important step in their shared efforts to prevent breast and ovarian cancer.

Pathologically, breast cancer is a complex disease with various subtypes, and genetic factors play a significant role in its development. The BRCA1 gene is one of the key genes associated with an increased risk of hereditary breast and ovarian cancer. Its main role is to act as a tumor suppressor gene, responsible for the repair of DNA damage and maintaining genomic stability within cells. When mutations occur in the BRCA1 gene, the repair mechanisms are impaired, leading to an accumulation of DNA damage and an increased risk of developing cancer.

The BRCA2 gene, similar to BRCA1, is also associated with hereditary breast cancer. Mutations in the BRCA2 gene impede DNA repair processes and increase the risk of developing breast and ovarian cancer, although to a lesser extent compared to BRCA1 mutations.

In terms of risk factors for breast cancer, both genetic and environmental factors play a role. In addition to BRCA1 and BRCA2 mutations, other risk factors include a personal or family history of breast or ovarian cancer, early onset of menstruation, late menopause, nulliparity or having a first child after the age of 30, hormone replacement therapy, exposure to ionizing radiation, and certain lifestyle factors such as alcohol consumption and obesity.

Interventions for preventive health management in individuals at risk for breast cancer include regular breast cancer screenings, such as mammography and clinical breast examinations, as well as self-breast exams. For individuals with a high-risk BRCA1 or BRCA2 mutation, additional preventive measures may include risk-reducing surgeries (prophylactic mastectomy or oophorectomy), chemoprevention with drugs like tamoxifen or raloxifene, and close monitoring by a multidisciplinary medical team specializing in cancer genetics.

It is crucial to emphasize that breast cancer prevention and management require a personalized approach, considering an individual’s specific risk factors, genetic profile, and overall health. Regular communication, education, and support are essential in empowering patients like Rachel to make informed decisions about their health and work towards preventive measures.

Share This Post


Order a Similar Paper and get 15% Discount on your First Order

Related Questions

Describe and critique a current article that relates to Nursing Assignment Help

Describe and critique a current article that relates to hospital financing and competitive practices in healthcare. (Article should be from a scholarly, peer-reviewed journal published within the last 3-5 years). Submit 1,000-1,500-word paper with a KU title page and reference page in a scholarly format. You are a medical professor

GCU Patient Preferences in Care Discussion Reply Nursing Assignment Help

please respond to the following discussion as a peer making a comment. Hello everyone, Integrating patient preferences and values with clinician expertise is essential when making evidence-based decisions. This approach leads to patient-centered care, improves treatment adherence, and enhances health outcomes. Patients’ unique values, beliefs, priorities, and circumstances can significantly

UM Administrator in Training Rotation Experience Report Nursing Assignment Help

Complete and Submit the Three Sections of the Report for the Assignment: AIT Experience: LTC Settings and Services Report Template (ATTACHED) APA: Include APA 7th Edition Formatted Reference Page. ALL RESPONSES IN PARAGRAPH FORM. Complete Section 1 of the Report Select the Long Term Care (LTC) Settings and Services: ALREADY

NYU Autoimmune Disease of Myelin Abstract Nursing Assignment Help

`The disease is called MS You should read Wikipedia “Immune System”, “Antibody”,  “Antigen”, “T  cell”, “B cell”, “Macrophage”, “Dendritic cell”  for writing your abstract. It would also be good to read the Wikipedia article on MS.  The purpose of writing an abstract is to condense the material you have read

Within the Professions of Psychology Paper Nursing Assignment Help

PSY 540 Final Project Guidelines and Rubric Overview Within the professions of psychology, it can be typical for you to work on proposals for programs, studies, or new initiatives. For example, you may work for a university that regularly partners with foundations and corporations to identify grant opportunities for projects

Professional Ethics Instructions Baccalaureate education Nursing Assignment Help

Professional Ethics Instructions Baccalaureate education includes the development of professional values and value-based behavior (AACN, 2008). Ethics define professional ethics and their importance in the healthcare environment. The American Nurses Association has approved 13 standardized languages that support nursing care.  The benefits of standardized language include: better communication among nurses

Select one of the following populations: Aging Nursing Assignment Help

Select one of the following populations: Aging Population Homelessness Migrant Workers LGBTQIA+ Other Identified Vulnerable Populations from Your Reading Then complete the following steps for your discussion post: Identify which vulnerable population you have chosen to use for this post and describe what this vulnerable population looks like in your

WGU Population Health Data Analysis Paper Nursing Assignment Help

In this course, you learned that Informatics for Transforming Nursing Care integrates nursing science with multiple information and analytical sciences to identify, define, manage, and communicate data, information, knowledge, and wisdom in nursing practice. This provides knowledge and skills to apply informatics concepts, communications, and data critical to facilitating interprofessional

Professional EthicsInstructions Baccalaureate education Nursing Assignment Help

Professional EthicsInstructions Baccalaureate education includes the development of professional values and value-based behavior (AACN, 2008). Ethics define professional ethics and their importance in the healthcare environment. The American Nurses Association has approved 13 standardized languages that support nursing care.  The benefits of standardized language include: better communication among nurses and

HSA 599 SU Public Health Emergencies Discussion Nursing Assignment Help

I’m working on a health & medical discussion question and need the explanation and answer to help me learn. Discuss a life-threatening event or a natural disaster in your community, such as a severe weather event, terrorist attack, or other type of public health emergency. Examine an overall strategy that

Develop a literature map or a visual representation of the Nursing Assignment Help

Develop a literature map or a visual representation of the Public Health Informatics literature.  Also include a powerpoint presentation explaining the literature map with the slides Constructing a literature map helps you: develop an understanding of the key issues and research findings in the literature organize ideas see how different research studies